The Prognostic Effect s of Pulmonary Hypertension on Hypertensive Heart Failure in Native African Population
The Prognostic Effect s of Pulmonary Hypertension on Hypertensive Heart Failure
in a Native African Population
Hypertension which occurs in 20-25% of adult Nigerian population is the most prevalent cardiovascular risk factor in this population group. One of the commonest complications of hypertension in this population group is heart failure, and accounts for about 60% of heart failure burden in this population similar to the findings in Heart of Soweto Study. Most of the studies carried in the past concentrated only on left ventricular function at the detriment of the right ventricle. There is hardly any study that has assessed the prevalence and effects of right ventricular function and pulmonary hypertension on the outcome of hypertensive heart failure in this population group. We therefore decided to assess the prevalence and effect of right ventricular function and pulmonary hypertension on the prognosis of hypertensive heart failure in Nigerian subjects.
With knowledge of previous studies, we hypothesised that pulmonary hypertension will adversely affect the prognosis of hypertensive heart failure in these subjects.
Our aims and objectives are: (1) to evaluate the prognostic effect of pulmonary hypertension in Nigerian subjects with hypertensive heart failure (2) to determine the prevalence of pulmonary hypertension in a cohort of Nigerian subjects with hypertensive heart failure and ( 3) to determine if pulmonary hypertension increases serum levels of brain natriuretic peptide and uric acid in Nigerian subjects with hypertensive heart failure
The study shall be prospective and observational. It shall be conducted at the Cardiology Unit, Department of Medicine, University of Abuja Teaching Hospital, Gwagwalada, Abuja in collaboration with the Hatter Institute, University of Cape Town, South Africa.
